Skip Ribbon Commands
Skip to main content

​​​Current Research Trials

Congestive Heart Failure:

Atmosphere—comparison of Tekturna® vs ACE inhibitor vs combination. Primary investigator: Cara East MD

Biomarkers in CHF—a panel of 4 markers followed monthly to see if can guide therapy. Primary investigator: Peter McCullough MD

HeartMate III—implantation of HeartMate III LVAD, compared to HeartMate II LVAS, for refractory, left heart failure. Primary investigator: Brian Lima MD

HeartMate PHP—study to evaluate the HeartMate PHP in subjects with cardiogenic shock. Primary investigator: Shelley Hall MD

HOST-48—a long-term follow-up of patients who had received autologous stem cells via chest surgery. Primary investigator: Cara East MD

INTERMACS—national registry for mechanical circulatory support. Primary investigator: Shelley Hall MD

ixCELL—autologous stem cells, expanded over 2 weeks, delivered to the heart via a catheter-based system (NOGA) for CHF. Primary investigator: Cara East MD

Relax—serelaxin infusion (a mimic of endogenous relaxin) in acute, decompensated CHF. Primary investigator: Cara East MD

Renew—autologous stem cells delivered to the heart via a catheter-based system (NOGA) for angina. Primary investigator: Cara East MD

Roadmap—observational study of patients who received the HeartMate II LVAD. Primary investigator: Shelley Hall MD

Serca2a—gene therapy study, with genes implanted into the LV at the time of LVAD implantation. Primary investigator: Brian Lima MD

SSI—driveline silicone skin interface registry, to look at factors that may lead to driveline infections. Primary investigator: Shelley Hall MD



Pulmonary hypertension:

PIPF13—a study to determine the efficacy of pirfenidone in interstitial lung disease (usual interstitial pneumonitis). Primary investigator: Randy Rosenblatt MD

Macitentan Phase IV study—an outcomes study of this drug, approved last fall. Primary investigator: Jon Kuiper MD

Prospect—a registry for patients with primary pulmonary hypertension, who receive treatment with RTS epoprostenol. Primary investigator: Jon Kuiper MD

Symphony—study of a questionnaire specific for pulmonary hypertension patients. Primary investigator: Jon Kuiper MD​